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Diuretic Equivalency Converter

Convert between loop diuretics with route-aware dosing and bioavailability context.

Route
mg
DrugIVPO
Furosemide40mg80mg
Torsemide40mg40mg
Bumetanide2mg2mg

Bioavailability matters here

Furosemide IV:PO = 1:2 (~50% oral bioavailability, worse with gut edema). Torsemide and bumetanide are 1:1.

Quick reference

  • Furosemide 40 mg PO = 20 mg IV = Torsemide 20 mg = Bumetanide 1 mg
  • Furosemide bioavailability: ~50% (highly variable, worse with gut edema)
  • Torsemide bioavailability: >80%
  • Bumetanide bioavailability: ~80%

TRANSFORM-HF (JAMA 2023) showed no significant difference in all-cause mortality between torsemide and furosemide in HF. The DOSE trial (NEJM 2011) found no difference between continuous infusion and intermittent bolus dosing.

References

  1. 01DOSE Trial (NEJM 2011)
  2. 02TRANSFORM-HF (JAMA 2023)
  3. 03UpToDate: Loop diuretic dose equivalents
  4. 04BMJ 2019: Loop diuretics in oedema
Updated 2026-04-19Report an error

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